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The Daily Insight

What is a Lentigene

Author

Marcus Reynolds

Updated on April 27, 2026

Solar lentigines (len-TIJ-ih-neez) are flat spots of increased pigmentation. They are usually tan, brown or dark brown and darker than freckles. Solar lentigines have oval to round shapes and vary in size. They usually appear on areas most exposed to the sun, such as the scalp, face, hands, arms and upper trunk.

Are lentigines the same as freckles?

The main difference between a freckle and a solar lentigo is that in a freckle only the amount of pigment being produced by melanocytes is increased, rather than the actual number of cells. Alternative names: Liver spot, old age spot, senile freckle, sun spots (singular: lentigo).

What does lentigo look like?

The visual symptoms of lentigo maligna melanoma are very similar to those of lentigo maligna. Both look like a flat or slightly raised brown patch, similar to a freckle or age spot. They have a smooth surface and an irregular shape. While they’re usually a shade of brown, they can also be pink, red, or white.

What is the significance of lentigines?

Multiple clinical and etiologic varieties exist. The distinction of a lentigo from other melanocytic lesions (eg, melanocytic nevi, melanoma) and its role as a marker for ultraviolet damage and systemic syndromes is of major significance.

Is a lentigo a freckle?

A lentigo is a pigmented flat or slightly raised lesion with a clearly defined edge. Unlike an ephelis (freckle), it does not fade in the winter months. There are several kinds of lentigo. The name lentigo originally referred to its appearance resembling a small lentil.

What does solar lentigines look like?

Solar lentigines (len-TIJ-ih-neez) are flat spots of increased pigmentation. They are usually tan, brown or dark brown and darker than freckles. Solar lentigines have oval to round shapes and vary in size. They usually appear on areas most exposed to the sun, such as the scalp, face, hands, arms and upper trunk.

Why are they called liver spots?

They tend to increase in number with age and are more prominent in fair-skinned people. They may be called liver spots because they were once thought to be a sign of a malfunctioning liver and they are often dark red or brown, the color of liver.

What is the difference between a nevus and lentigo?

Lentigo and junctional nevus can look like a freckle. Actinic lentigo does not darken with sun exposure and is acquired later in life. In contrast, freckles darken after sun exposure and are present from early childhood. Lentigo simplex is acquired in childhood, but the lentigines are not confined to sun-exposed skin.

Are Lentigines common?

Lentigines, or liver spots, are benign lesions that occur on the sun-exposed areas of the body. The backs of hands and face are common areas. The lesions tend to increase in number with age, making them common among the middle age and older population. They can vary in size from 0.2 to 2 cm.

Is a nevus a mole?

Most people continue to develop new moles until about age 40. In older people, common moles tend to fade away. Another name for a mole is a nevus. The plural is nevi.

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Is lentigo maligna cancerous?

What is lentigo maligna? Lentigo maligna is one type of the earliest stage of a skin cancer called melanoma. The word ‘melanoma’ comes from the Greek word ‘melas’, meaning black. Melanin is the dark pigment that gives the skin its natural colour and is made in the skin by pigment cells called melanocytes.

How do you get rid of lentigo simplex?

  1. medicines such as bleaching creams containing hydroquinone or retinoids (tretinoin)
  2. chemical peels.
  3. laser or intense pulse light therapy to destroy melanocytes.
  4. freezing (cryotherapy) to destroy melanocytes.

Is lentigo maligna melanoma cancerous?

Lentigo maligna (LM) and lentigo maligna melanoma (LMM) are types of skin cancer. They begin when the melanocytes in the skin grow out of control and form tumors.

What are big freckles called?

The most common type, solar lentigines, arise in middle age and result from sun damage. They are most often found on the face and hands, and they are larger and more defined than freckles. Other types of lentigo include ink spot lentigo and lentigo simplex.

Is lentigo a cosmetic?

Senile lentigo–cosmetic or medical issue of the elderly population. Coll Antropol.

Are liver spots bad?

LIVER SPOTS: The official name for liver or age spots is “lentigines” from the Latin for “lentil.” These are flat, brown with rounded edges and are larger than freckles. They are not dangerous.

Are liver spots harmful?

Liver spots are not dangerous to your health. They are permanent skin changes that affect how your skin looks.

Can liver spots turn cancerous?

These spots are called “actinic lentigines,” which are more commonly referred to as sun spots, age spots, or liver spots. These small, gray-brown spots aren’t a type of skin cancer. They also don’t progress to become skin cancer and don’t require any treatment.

How do you get rid of liver spots?

  1. Medications. Applying prescription bleaching creams (hydroquinone) alone or with retinoids (tretinoin) and a mild steroid might gradually fade the spots over several months. …
  2. Laser and intense pulsed light. …
  3. Freezing (cryotherapy). …
  4. Dermabrasion. …
  5. Microdermabrasion. …
  6. Chemical peel.

What is a benign solar lentigo?

Solar lentigo is a harmless patch of darkened skin. It results from exposure to ultraviolet (UV) radiation, which causes local proliferation of melanocytes and accumulation of melanin within the skin cells (keratinocytes). Solar lentigos or lentigines are very common, especially in people over the age of 40 years.

Why am I suddenly getting age spots?

Age spots are caused by overactive pigment cells. Ultraviolet (UV) light speeds up the production of melanin, a natural pigment that gives skin its color. On skin that has had years of sun exposure, age spots appear when melanin becomes clumped or is produced in high concentrations.

What causes Dermatofibroma?

Dermatofibromas are caused by an overgrowth of a mixture of different cell types in the dermis layer of the skin. The reasons why this overgrowth occurs aren’t known. The growths often develop after some type of small trauma to the skin, including a puncture from a splinter or bug bite.

What does melanoma look like on your face?

Border that is irregular: The edges are often ragged, notched, or blurred in outline. The pigment may spread into the surrounding skin. Color that is uneven: Shades of black, brown, and tan may be present. Areas of white, gray, red, pink, or blue may also be seen.

Why am I suddenly getting lots of moles?

The cause of moles isn’t well understood. It’s thought to be an interaction of genetic factors and sun damage in most cases. Moles usually emerge in childhood and adolescence, and change in size and color as you grow. New moles commonly appear at times when your hormone levels change, such as during pregnancy.

What does Stage 1 melanoma look like?

Stage I melanoma is no more than 1.0 millimeter thick (about the size of a sharpened pencil point), with or without an ulceration (broken skin). There is no evidence that Stage I melanoma has spread to the lymph tissues, lymph nodes, or body organs.

What is an angry mole?

An inflamed mole (nevus) can become more red in appearance and begin to swell, making it look like it has grown. This tends to occur from irritation when healthy moles are rubbed or injured, such as with habits like shaving.

What is the 5-year survival rate for stage 0 melanoma?

Stage 0: The 5-year relative survival rate is 97%. Stage I: The 5-year survival rate is 90-95%. If a sentinel node biopsy yields findings of melanoma in the lymph nodes, the 5-year survival is approximately 75%.

Do melanomas always get bigger?

They look like a freckle, but they’re usually larger, darker and stand out more than a normal freckle. They can gradually get bigger and may change shape. At a later stage, they may grow downwards into the deeper layers of skin and can form lumps (nodules).

What is the most aggressive type of melanoma?

Nodular melanoma – This is the most aggressive form of cutaneous melanoma.

Can lentigo go away?

Lentigines or lentigos are like freckles, Barankin says. But where a true freckle will fade in the winter when sun exposure is limited, these spots do not go away on their own. Lentigos are the result of sun exposure.

What causes liver spots on hands and arms?

Age spots, which are sometimes called liver spots or solar lentigines, happen after exposure to ultraviolet (UV) light, says dermatologist Amy Kassouf, MD. They can be tan, brown or black, vary in size and usually appear on the areas most exposed to the sun such as the face, hands, shoulders and arms.